Lykes may refer to:
Surname: Brinton Lykes (born 1949), American psychologist Chris Lykes (born 1998), American professional basketball player
Businesses: Lykes Brothers, private company founded in Florida in 1910 Lykes Brothers Steamship Company, cargo shipping company during the 20th century Lykes Meat Group sells meat products such as ham, ground pork, pork chops, bacon, lunch meat Lykes Coastwise Line, Inc., passenger and cargo shipping line founded in 1943 in California, United States
Infrastructure: Lykes Palmdale Airport (FAA LID: FL73) is a small private airport in Glades County, Florida, United States Lykes Building, skyscraper located in downtown Tampa, Florida, United States
Ships: SS Almeria Lykes (1920) MV Almeria Lykes (1972) SS Almeria Lykes (1940) SS Doctor Lykes SS Jean Lykes SS Louise Lykes SS Louise Lykes (1941) SS Nancy Lykes SS Tillie Lykes (1972)