Roshan Sethi is a Canadian physician, writer and film director, currently working in the United States.Aparita Bhandari, "Calgary filmmaker dreams up a big gay Bollywood wedding in new rom-com". CBC Arts, April 4, 2025. In 2026, he published his debut novel, The Simp: A Novel Without a Hero.

Background Originally from Calgary, Alberta, Sethi is of Indian origin. He worked as a radiation oncologist at Brigham and Women's Hospital in Boston, Massachusetts, before taking some time off to write for the medical drama series Code Black.Jamie Ducharme, "This Brigham and Women’s Resident Traded Hospitals for Hollywood". Boston Magazine, August 15, 2016.

He was a co-creator of the American medical drama series The Resident, which ran for six seasons, 2018–2023.Jake Dee, "This 2018 Fox Series Is the Best Medical Drama Since House". Movieweb, April 7, 2024.

He still practices medicine part-time.

Film career He released his debut film 7 Days in 2021. The romantic comedy film was based in part on his experiences as a medical professional in the early days of the COVID-19 pandemic, in 2021."The Cast and Crew of ‘7 Days’ on Reliving Quarantine as a Romantic Comedy". Variety, April 4, 2022. The film won the 2022 Independent Spirit Award for Best First Feature.

In 2022, he was a co-writer of the screenplay for Call Jane.Stephanie Zacharek, "Elizabeth Banks Plays a Suburban Mom Who Finds Her Purpose in the Abortion Drama Call Jane". Time, October 27, 2022.

He directed the films World's Best in 2023,Michael Nordine, "‘World’s Best’ Review: Roshan Sethi’s Coming-of-Age Dramedy Isn’t Exactly a Mic Drop". Variety, June 23, 2023. and A Nice Indian Boy in 2024.Proma Khosla, "‘A Nice Indian Boy’ Review: This Charming, if By-the-Book Interracial Rom-Com, Packs a Bollywood Twist". IndieWire, March 31, 2025. "World's Best" was nominated for a Children's and Family Emmy in 2025.

In 2026, Sethi wrote and directed The Surgeon, starring Michelle Yeoh, set for its world premiere at the 2026 Toronto International Film Festival.

Personal life Sethi came out as gay at age 30. He is married to actor Karan Soni, who has been a credited cowriter and/or cast member in all of Sethi's films to date.

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