Iacobellis is a surname. Notable people with the surname include:
Angela Iacobellis (1948–1961), Italian girl and Servant of God Jorge Iacobellis (born 1956), Argentine drummer, tour promoter, and producer Marco Iacobellis (born 1999), Argentine footballer Sam F. Iacobellis (1929–2016), American engineer
See also Iacobelli, another surname