2C-T-27, also known as 4-benzylthio-2,5-dimethoxyphenethylamine, is a psychedelic drug of the phenethylamine and 2C families.
Use and effects 2C-T-27 has been reported to produce hallucinogenic effects in humans. Its dose was reported by Daniel Trachsel to be 80mg or more orally and no duration was listed.
Interactions
Pharmacology Pharmacodynamics In addition to the serotonin 5-HT2A receptor, 2C-T-27 interacts with the serotonin 5-HT2C receptor. It showed higher affinity for the serotonin 5-HT2A receptor than any other 2C drug (Ki = 1.6nM), but its activational potency and efficacy were among the lowest ( = 26nM; = 27%).
The drug produces the head-twitch response (HTR), a behavioral proxy of psychedelic effects, in rodents. However, the HTR induced by 2C-T-27 is relatively weak.
Chemistry Analogues Analogues of 2C-T-27 include 2C-T-6, 2C-T-31, and 2C-T-33, among others.
History 2C-T-27 was first synthesized and described by Daniel Trachsel in 2003.
Society and culture Legal status Canada 2C-T-27 is a controlled substance in Canada under phenethylamine blanket-ban language.
See also 2C (psychedelics) 2C-T-8 3C-BZ Benzscaline (BZ) 2C-Ph
References
External links 2C-T-27 - isomer design