Pierro is an Italian surname. Notable people with the surname include:
Albino Pierro (1916–1995), Italian poet Bill Pierro (1926–2006), American baseball player Casey Pierro-Zabotel (born 1988), Canadian former ice hockey player Gerardo Pierro (1935–2025), Italian Roman Catholic archbishop Marina Pierro (born 1956), Italian actress, model, writer, and film director Nahuel di Pierro (born 1984), Argentine operatic bass Simon Pierro (born 1978), German magician and TV presenter
See also Adriano De Pierro (born 1991), Swiss footballer Dipierro, several people