Seetharam is a surname and a given name. Notable people with the name include:
Palakala Seetharam Bhat (1931–2017), Kannada writer M. K. Seetharam Kulal (1940–2019), Indian Tulu-Kannada dramatist Seetharam Prabhu (born 1964), Indian cricket umpire M. R. Seetharam, Indian politician, entrepreneur, educationist and philanthropist Nikhil Seetharam (known as Kromatik), Canadian composer and record producer T. N. Seetharam (born 1948), Kannada film and TV serial director, actor and screenwriter T. P. Seetharam, Indian Civil servant, Indian ambassador to United Arab Emirates Thammineni Seetharam, Indian politician from the YSR Congress Party
See also Seetharam Benoy Case No. 18, a 2021 Indian Kannada-language suspense thriller