Trajano is a surname and given name. Notable people with the name include:

Trajano Boccalini (1556–1613), Italian satirist José Trajano (born 1946), Brazilian journalist and writer José Trajano Mera (1862–1919), Ecuadorian poet, playwright and diplomat Archimedes Trajano (1956–1977), Filipino student activist Frederico Trajano (born 1976), CEO of Brazilian retail company Magazine Luiza Luiza Trajano (born 1948), Brazilian billionaire businessperson Tagore Trajano, lawyer and professor from Salvador, Bahia, Brazil

See also Trajano de Moraes, municipality in the Brazilian state of Rio de Janeiro Ara de Trajano, Roman inscription on a granite boulder in Caldas das Taipas, Braga District, Portugal, dated 103 Brazilian cruiser Trajano, a cruiser-type warship belonging to the Imperial Brazilian Navy from 1873