HMB may refer to:
Compounds β-Hydroxy β-methylbutyric acid, , a metabolite of the essential amino acid leucine, synthesized in the human body Human Melanoma Black, a monoclonal antibody
Languages Humburi Senni language, spoken in Burkina Faso and Mali
Places Half Moon Bay, California, city in the United States
Sports Historical medieval battles, a modern sport
Other Hawkeye Marching Band, the marching band for the University of Iowa Hukbong Mapagpalaya ng Bayan, the new name used by the Hukbalahap in their later rebellion against the Third Philippine Republic HabibMetro, a Swiss multinational bank in Pakistan Heavy menstrual bleeding, a menstrual condition Host Memory Buffer, an optional feature in version 1.2 of the NVMe specification, which allows SSDs to utilize the DRAM of the host machine His/Her Magesty's Barque