Yokoe () is a Japanese surname. Notable people with the surname include:
Kaneo Yokoe (横江 金夫, 1934–2025), Japanese politician Ryuji Yokoe (横江 竜司, born 1978), Japanese motorcycle racer
Other uses Yokoe Station, a railway station in the Japanese town of Tateyama Tōdai-ji Yokoe Shōen, an archaeological site in the Japanese Hokuriku region