Penfield may refer to:

Places United States Penfield, Georgia, an unincorporated community Penfield, Illinois, a census-designated place Penfield, New York, a town Penfield Township, Lorain County, Ohio Penfield, Pennsylvania, an unincorporated community Penfield, Haverford Township, Pennsylvania, an unincorporated community Penfield Reef, extending from Fairfield, Connecticut to Long Island Sound

Australia Penfield, South Australia, a suburb of Adelaide

Education Penfield Academy, Quebec, Canada, a former school Penfield Central School District, New York Penfield High School, Penfield, New York

People Penfield (surname), a list of people with the name Penfield Tate II (born 1931), the first and only black mayor of Boulder, Colorado Penfield Tate III (born 1956), American politician and lawyer

Transportation Penfield railway line, Adelaide, South Australia Penfield 1 railway station Penfield 2 railway station Penfield 3 railway station Penfield station (SEPTA), in Haverford Township, Pennsylvania

Other uses Doctor Penfield Avenue, Montreal Louis Penfield House, Ohio, built by Frank Lloyd Wright Penfield Library, State University of New York at Oswego Penfield Outdoor Apparel, a Massachusetts clothing company

See also Penfield homunculus, a distorted representation of the human body Prix Wilder-Penfield, an award for biomedicine research Pinfield, a surname