The Church of St Mary and St Nicholas and variations on this name may refer to:
Churches in England St Mary and St Nicolas, Spalding, Lincolnshire Church of St Mary and St Nicholas, Littlemore, Oxfordshire Church of St Nicholas and the Blessed Virgin Mary, Stowey, Somerset Church of St Mary & St Nicholas, Leatherhead, Surrey Church of St Mary and St Nicholas, Wilton, Wiltshire
Churches in Wales St Mary's and St Nicholas's Church, Beaumaris, Anglesey