The 2022 Tufts Jumbos football team represented Tufts University as a member of the New England Small College Athletic Conference (NESCAC) during the 2022 NCAA Division III football season. Led by 12th-year head coach Jay Civetti, the Jumbos compiled a record of 6–3 with all games played against conference opponents, tying for third place in the NESCAC. Tufts played home games at Ellis Oval in Medford, Massachusetts.
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