Giles is an unincorporated community in Kemper County, Mississippi, United States.

Giles is located on Mississippi Highway 16, east of Scooba.

History Jacob Giles built a plantation here in 1835.

A Mississippi historical marker is located at the Neville-Giles Cemetery in Giles.

The population in 1900 was 45.

Notable people Shepherd S. Neville, planter and merchant in Giles; represented Sumter County, Alabama, in 1882 state legislature.

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