The 2024–25 Winthrop Eagles women's basketball team represented Winthrop University during the 2024–25 NCAA Division I women's basketball season. The Eagles, led by fifth-year head coach Semeka Randall Lay, played their home games at the Winthrop Coliseum in Rock Hill, South Carolina as members of the Big South Conference.

Previous season The Eagles finished the 2023–24 season 14–15, 8–8 in Big South play, to finish in a three-way tie for fourth place. They would be defeated by Radford in the quarterfinals of the Big South tournament.

Roster

Schedule and results

!colspan=12 style=""| Non-conference regular season

!colspan=12 style=""| Big South regular season

!colspan=12 style=""|

Sources:

References