Paul Kane (1810–1871) was an Irish-Canadian painter.

Paul Kane may also refer to:

Paul Kane (writer) (born 1973), British science fiction writer Paul Kane (footballer) (born 1965), Scottish footballer Paul Kane (entrepreneur), British technology company executive Paul Kane (poet) (born 1950), American poet, critic and scholar Paul Kane (rugby union), New Zealand priest and international rugby union player Paul Kane, a former stage name of Paul Simon (born 1941)

See also Paul Kane High School, a school in St. Albert, Alberta Paul Cain (disambiguation)