Kirke Eskilstrup is a small railway town in Holbæk Municipality in Region Zealand, Denmark. As of 1 January 2026 it has a population of 638.BY3: Population 1. January by urban areas, area and population density The Mobile Statbank from Statistics Denmark It is located about 18 km south of Holbæk and about 20 km north of Ringsted.

Kirke Eskilstrup is served by Kirke Eskilstrup railway station located on the Tølløse Line between and .

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