Sæthre is a surname. Notable people with the surname include:
Børre Sæthre (born 1967), Norwegian artist Ingrid Camilla Fosse Sæthre (born 1978), Norwegian football player Ståle Steen Sæthre (born 1993), Norwegian football player and coach Torunn Fossli Sæthre (born 1970), Norwegian orienteering competitor