Yaghjian, or Yahjian (, derived from Turkish yağcı [yağ "fat/oil/butter/lard" + cı "agentive/profession suffix"], meaning "oil/butter seller") is a surname of Armenian origin. Notable people with the surname include:

Arthur D. Yaghjian (born 1943), American electrical engineer Candy Yaghjian Waites (born 1943), American former politician Edmund Yaghjian (1903–1997), Armenian-born American painter, educator Kurt Yaghjian (born 1951), American actor