Sotiriou is a surname. Notable people with the surname include:
Andreas Sotiriou (born 1968), Cypriot footballer Dido Sotiriou (1909–2004), Greek novelist, journalist, and playwright Dimitrios Sotiriou (born 1987), Greek footballer Evangelia Sotiriou (born 1980), Greek rhythmic gymnast Georgios Sotiriou (1880–1965), Greek archaeologist, byzantinologist and university professor Katerina Sotiriou (born 1984), Greek basketball player Pieros Sotiriou (born 1993), Cypriot footballer Ruel Sotiriou (born 2000), Cypriot footballer Zisis Sotiriou, Greek revolutionary