de Anda or DeAnda is a Spanish surname. Notable people with the surname include:
Alfonso de Anda (born 1974), Mexican television host Agustín de Anda (1933–1960), Mexican singer Carlos de Anda (1908–1995), Mexican sprinter Cuauhtémoc Anda Gutiérrez (born 1938), Mexican politician Francisco Gabriel de Anda (born 1971), Mexican footballer and sports analyst Francisco Javier Valdés de Anda (born 1956), Mexican politician Gilberto Gazcón de Anda (1929–2013), Mexican film director, screenwriter and producer James DeAnda (1925–2006), American judge Pablo de Anda Padilla (1830–1904), Mexican Catholic priest Paula DeAnda (born 1989), American singer Pedro de Anda (–1619), Spanish conquistador Raúl de Anda (1908–1997), Mexican film director, screenwriter and film producer Rodolfo de Anda (1943–2010), Mexican actor Simón de Anda y Salazar (1709–1776), Spanish politician Tamara De Anda (born 1983), Mexican blogger and journalist