Diego Ortiz ( – ) was a Spanish composer and music theorist.

Diego Ortiz may also refer to:

Diego Ortiz de Calzadilla (died 1519), Castilian bishop, theologian and astronomer in Portuguese service Diego Ruiz Ortiz (1532–1571), Spanish friar and missionary in Peru, regarded as a martyr , Spanish conquistador and governor of the Río de la Plata (1576–1577) Diego Ortiz de Zúñiga (died 1680), Spanish historian Diego Ortiz Parrilla (died 1775), Spanish soldier, politician, explorer and cartographer