Zygothuria is a genus of sea cucumbers belonging to the family Mesothuriidae. The genus has a cosmopolitan distribution.
Species The following species are recognised in the genus Zygothuria: Mesothuria candelabri Hérouard, 1923 Mesothuria connectens R. Perrier, 1898 Mesothuria lactea Théel, 1886 Mesothuria marginata Sluiter, 1901 Mesothuria oxysclera R. Perrier, 1899 Mesothuria thomsoni Théel, 1886
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