De Saram is a surname. Notable people with the surname include:
Carole De Saram, American feminist and women's rights activist Fredrick de Saram, Sri Lankan lawyer, cricket captain, and military officer Indika de Saram, Sri Lankan cricketer John De Saram, Sri Lankan lawyer and diplomat Lakshman Joseph de Saram, Sri Lankan composer and musician Rohan de Saram, British and Sri Lankan cellist Rohan Joseph de Saram, Sri Lankan pianist and conductor R. S. de Saram, Sri Lankan educationist and clergyman