Familial Alzheimer-like prion disease is an exceptionally rare inherited prion disease. Its name comes from its presentation, which is similar to Alzheimer's disease.
Symptoms This disease is unusual in that, unlike other prion diseases, it does not present with myoclonus or ataxia. Instead, the initial presentation involves anxiety, depression, and memory impairment before progression into dementia. This dementia has a slow course, also atypical for a prion disease, and will eventually lead to the death of the patient years after onset.
References
External links Familial Alzheimer-like prion disease at the Genetics and Rare Diseases Information Centre (GARD)