Kgosietsile is a masculine given name, and is an alternative form of Kgosi. Notable people with the name include:
Kgosi Letlape (born Tebogo Kgosietsile Solomon Letlape), South African ophthalmologist Kgosietsile Mampori, Motswana footballer Kgosi Ntlhe (born Kgosietsile Ntlhe; 1994), South African footballer King Ndlovu (born Kgosietsile King Ndlovu; 1993), South African footballer