ORG-24598 is a selective inhibitor of the type 1 glycine transporter.
Potential uses
Alcohol use disorder A test in rats has shown that combining varenicline, bupropion, and an indirect glycine agonist (such as ORG-24598) could be beneficial for treatment of alcohol use disorder.
Schizophrenia Studies have shown that glycine re-uptake inhibitors selective for the type 1 transporter may be useful for the treatment of certain schizophrenia symptoms.
References