The Battle of Guayacanes (Spanish: Batalla de Guayacanes de 1863) was a battle of the Dominican Restoration War that took place on August 22, 1863 and lasted several hours. A Spanish column advancing toward Santiago was engaged by Dominican forces near Guayacanes. Dominicans opened the battle with rifle fire; Spanish troops launched several assaults on Dominican defensive positions but were repelled, and the battle devolved into hand-to-hand combat with bayonets and machetes. After suffering casualties, the Spanish force withdrew toward Santiago.
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