Pirotta and Pirrotta are Italian surnames. Notable people with these names include:
Pirotta Angelo Pirotta (1894–1956), Maltese philosopher Luigi Pirotta (1900–1971), Italian archivist and chief scout Pietro Romualdo Pirotta (1853–1936), Italian botanist Saviour Pirotta (born 1958), Maltese-born British author and playwright Vanessa Pirotta, Australian wildlife scientist
Pirrotta Nino Pirrotta (1908–1998), Italian musicologist Vincenzo Pirrotta (born 1942), Italian-born American biologist