DYRK is an FM radio station in Cebu City, Philippines known as 96.3 WRocK. It may also refer to:

Science and technology DYRK1A, protein-coding gene in humans DYRK1B, protein-coding gene in humans DYRK2, protein-coding gene in humans DYRK3, protein-coding gene in humans

Television and film Dyrk jorden!, a 1936 film Dyrk Magz, DC Comics character also known as Magno