Jorge Guzmán may refer to:
Jorge Guzmán (baseball) (born 1996), Dominican baseball player Jorge Guzmán (footballer, born 1980), Chilean footballer Jorge Guzmán (footballer, born 2003), Mexican footballer Jorge Guzmán Montt (1879–1929), Chilean politician Jorge Guzmán (wrestler) (born 1963), Mexican luchador enmascarado known as El Hijo del Santo Jorge Guzmán Zepeda, Chilean politician