Ssentongo is a surname. Notable people with the surname include:
Dickson Ssentongo (1981–2010), Ugandan radio journalist Henry Ssentongo (1936–2019), Ugandan Roman Catholic priest Jimmy Spire Ssentongo (born 1979), Ugandan professor Moses Ddiba Ssentongo, Ugandan military officer Nabulya Theopista Ssentongo (born 1951), Ugandan politician Robert Ssentongo (footballer) (born 1988), Ugandan footballer Robert Ssentongo (surgeon), Ugandan plastic surgeon