Kobena is both a given name and a surname. Notable people with the name include:

Kobena Eyi Acquah (born 1952), Ghanaian lawyer Kobena Amed (born 1997), Ivorian footballer Kobena Mercer (born 1960), British art historian Nouhoum Kobéna (born 1985), Beninese footballer Robert Kobena Dentu, Ghanaian minister