P80 may refer to:
Automobiles BMW P80, a family of Formula One engines Toyota Starlet (P80), a Japanese car Volvo P80 platform, a Swedish mid-size automobile platform WM P80, a French prototype racing car
Other vehicles P80 (rocket stage), a rocket engine , a corvette of the Indian Navy Lockheed P-80 Shooting Star, an American jet fighter Pottier P.80, a French sport aircraft
Other uses Nikon Coolpix P80, a digital camera P80, a national road of Latvia Pestivirus NS3 polyprotein peptidase, an enzyme p80, a subunit of the protein Katanin
See also Pistole 80, a military designation for the Glock pistol Polymer80, an American firearms manufacturer