The 1st federal electoral district of Zacatecas () is one of the 300 electoral districts into which Mexico is divided for elections to the federal Chamber of Deputies and one of four such districts in the state of Zacatecas.

It elects one deputy to the lower house of Congress for each three-year legislative period, by means of the first-past-the-post system. Votes cast in the district also count towards the calculation of proportional representation ("plurinominal") deputies elected from the second region.

The current member for the district, elected in the 2024 general election, is of the National Regeneration Movement (Morena).

District territory + Evolution of electoral district numbers 1974 1978 1996 2005 2017 2023 Zacatecas 4 5 5 4 4 4 Chamber of Deputies 196 300 Sources:

Under the 2023 districting plan adopted by the National Electoral Institute (INE), which is to be used for the 2024, 2027 and 2030 federal elections, the 1st district of Zacatecas covers 465 electoral precincts () across eight municipalities in the western portion of the state: Chalchihuites, Fresnillo, Jiménez del Teul, Juan Aldama, Miguel Auza, Saín Alto, Sombrerete and Valparaíso.

The head town (), where results from individual polling stations are gathered together and tallied, is the city of Fresnillo. The district reported a population of 416,468 in the 2020 census.

Deputies returned to Congress

+ Zacatecas's 1st district Election Deputy Party Term Legislature1961Alfonso Méndez Barraza1961–196445th Congress19641964–196746th Congress1967Calixto Medina Medina1967–197047th Congress1970 Raúl Rodríguez Santoyo1970–197348th Congress1973 Luis Arturo Contreras Serrano1973–197649th Congress1976Gustavo Salinas Íñiguez1976–197950th Congress19791979–198251st Congress1982Genaro Borrego Estrada1982–198552nd Congress1985Yrene Ramos Dávila1985–198853rd Congress1988Julián Ibargüengoytia Cabral1988–199154th Congress19911991–199455th Congress1994Yrene Ramos Dávila1994–199756th Congress1997José Eulogio Bonilla Robles 1997–200057th Congress2000Alfonso Elías Cardona2000–200358th Congress2003Guillermo Huízar Carranza2003–200659th Congress2006Susana Monreal Ávila2006–200960th Congress2009Gerardo Leyva Hernández2009–201261st Congress2012Adolfo Bonilla Gómez2012–201562nd Congress2015Benjamín Medrano Quezada José Luis Velázquez González2015–2018201863rd Congress2018Mirna Zabeida Maldonado Tapia 2018–202164th Congress2021Bennelly Hernández Ruedas2021–202465th Congress20242024–202766th Congress

Presidential elections + Zacatecas's 1st district Election District won by Party or coalition % 2018Andrés Manuel López Obrador Juntos Haremos Historia 50.94382024Claudia Sheinbaum Pardo Sigamos Haciendo Historia 48.4922

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