Velayudhan is both a given name and a surname. Notable people with the name include:
Velayudhan Govindan (died 2015), Indian cricketer Dakshayani Velayudhan (1912–1978), Indian politician P. K. Velayudhan (born 1946), Indian politician Prakash Velayudhan (), Indian cinematographer R. Velayudhan (1911–?), Indian politician
See also Dakshayani Velayudhan Award