Manchester is a surname. Notable people with the surname include:
Catherine Manchester (born 1957), New Zealand painter Devon Manchester (born 1989), New Zealand field hockey player Doug Manchester (born 1942), American real estate developer and newspaper owner Glen Manchester (born 1965), English innovator and entrepreneur Jeffrey Manchester (born 1971), American convicted spree-robber Melissa Manchester (born 1951), American singer-songwriter Roy C. Manchester (1887–1975), American Boy Scout executive Susan Manchester (born 1987), American politician in Ohio Tre Manchester (born 1992), American writer, director, and producer William Manchester (1922–2004), American historian and biographer Eric Manchester (1964–2023), American actor and model