Senaratne is a surname. Notable people with the surname include:
Akash Senaratne (born 1996), Sri Lankan cricketer Chathura Senaratne (born 1982), Sri Lankan politician Indika Senaratne (born 1986), Sri Lankan cricketer Loranee Senaratne (1913-2004), Sri Lankan diplomat Nipuna Senaratne (born 1993), English cricketer Rajitha Senaratne (born 1950), Sri Lankan dentist and politician Sisira Senaratne (1935–2015), Sri Lankan singer