Genesee Building/Hyatt Regency Hotel is a 15-story tall hotel building in Buffalo, New York that was built as the Hyatt Regency Hotel in 1922 by architects E.B. Green and William S. Wicks.

History The building was originally built as the Genesee Building in 1811 as a quick way-station for people like farmers carrying livestock, it wasn't until 1842 when it would be rebuilt as a 5-story tall brick hotel and then in 1881 it was remodeled into The Genesee Hotel.

In the 1980s the building was under-utilized but a local developer named Paul Snyder decided to incorporate the building into the Hyatt business.

On 1 June 2022, the building closed briefly after its closure in March 2022 after the COVID-19 pandemic which caused the building to lose a lot of revenue. but as of 2024 it is back in operation as Hyatt.

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