In neurobiology, spindle cell refers to:

Spindle neuron, also known as a von Economo neuron

In general medicine, a spindle cell may refer to the spindle-shaped cells that are found in certain types of tumor:

Inflammatory fibroid polyp Pigmented spindle cell nevus Spindle cell carcinoma Spindle cell lipoma Spindle cell sarcoma

See also Spindle apparatus (part of a cell)