Hambardzum (), also spelt Hambartsum and Ambartsum, is an Armenian masculine given name, meaning "ascension". Notable people with the given name include:
Hambardzum Arakelian (1865–1918), Armenian journalist, writer and public activist Hampartzoum Berberian (1905–1999), Armenian American composer, conductor and political activist Hampartsoum Boyadjian (1860–1915), Armenian fedayee and politician in the Ottoman Empire Hambardzum Galstyan (1955–1994), Armenian politician and historian Hambarsoom Grigorian (1893–1975), Armenian musician Hampar Kelikian (1899–1983), Armenian American orthopedic surgeon Hambartsum Khachanyan (1894–1944), Armenian actor Hampartsoum Limondjian (1768–1839), Ottoman Armenian composer Hambardzum Terteryan (1884–????), Armenian politician
See also Ambartsumian, a surname derived from this name