Charles McCullough may refer to:
Charles McCullough (Northern Ireland politician) (1923–2014), Northern Irish unionist politician Charles A. McCullough II (born 1978), American politician and civil rights activist Sir Charles McCullough (judge) (1931–2018), British barrister and judge Charlie McCullough (1866–1898), Major League Baseball pitcher
See also Charles S. McCullough House, a historic home in Darlington, Darlington County, South Carolina