Lomonaco is an Italian surname. Notable people with the surname include:
Francesco Lomonaco (1772–1810), Italian writer Juan Carlos Lomonaco (born 1969), Mexican musician Kevin Lomonaco (born 2002), Argentine footballer Mark LoMonaco (born 1971), American wrestler better known as Bubba Ray Dudley Michael Lomonaco (born 1955), American chef, restaurateur, and television personality Samuel J. Lomonaco Jr. (born 1942), American academic and mathematician Sebastián Lomonaco (born 1998), Argentine footballer Tommaso Lomonaco (1901–1992), Italian scientist