Anthonisz is a surname. Notable people with the surname include:

Adriaan Anthonisz (1527–1607), Dutch mathematician, surveyor, cartographer, and military engineer Cornelis Anthonisz (ca. 1505–1553), Dutch painter, engraver, and mapmaker

R. G. Anthonisz (1852–1930), Ceylonese lawyer, educationist, and civil servant Stefan Anthonisz (born 1963), Sri Lankan cricketer Vernon Anthonisz, Singaporean radio presenter