Nosipho is a given name. Notable people with the name include:
Nosipho Dastile (1938–2009), South African community and anti-apartheid activist Nosipho Dumisa (born 1988), South African writer, director and producer Nosipho Makamba-Botya, South African politician Nosipho Ntwanambi (1959–2014), South African politician, women's and human rights activist