Lopers 13 gang, also known as LPS or LPSX13, is a gang that was founded by Mexican Americans in Madison Park in Santa Ana, California in the 1970s or 1980s. It is the biggest gang in Santa Ana by territory.

Territory Lopers 13 has territory in Main Street, Minnie Street, First Street and Edinger Ave. In November 2016, eight suspected members of Lopers 13 were arrested in a coordinated law enforcement operation within or near this territory. The Santa Ana Police SWAT team served warrants at three locations near Standard Street and McFadden Avenue, seizing methamphetamine, cocaine, Xanax, and a rifle. The arrests targeted gang members allegedly involved in drug sales, conspiracy, and other crimes. The operation involved the Santa Ana Police gang unit, probation, the Orange County District Attorney's Office, and the FBI.

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