The Independent Spirit Award for Best Supporting Performance in a New Scripted Series is one of the annual Independent Spirit Awards to honor an actor who has delivered an outstanding supporting performance in a new scripted series.

In 2022, it was announced that the acting categories Best Female Performance in a New Scripted Series and Best Male Performance in a New Scripted Series would be retired and replaced with two gender neutral categories: Best Lead Performance in a New Scripted Series and Best Supporting Performance in a New Scripted Series.

Winners and nominees 2020s YearNomineesShowRoleNetwork 2022 Ayo Edebiri The Bear Sydney Adamu FX on HuluDanielle DeadwylerStation ElevenMiranda CarrollHBO MaxJeff HillerSomebody SomewhereJoelHBOGbemisola IkumeloA League of Their OwnClance MorganPrime VideoJanelle JamesAbbott ElementaryAva ColemanABCEbon Moss-BachrachThe BearRichard "Richie" JerimovichFX on HuluFrankie QuiñonesThis FoolLuisHuluSheryl Lee RalphAbbott ElementaryBarbara HowardABCMolly ShannonI Love That for YouJackie StiltonShowtimeTramell TillmanSeveranceSeth MilchickApple TV+2023Nick Offerman The Last of Us Bill HBOMurray Bartlett The Last of UsFrankHBOBillie EilishSwarmEvaPrime VideoJack FarthingRain DogsSelbyHBOAdina PorterThe ChangelingLillian KagwaApple TV+Lewis PullmanLessons in ChemistryCalvin EvansBenny SafdieThe CurseDougie SchecterShowtimeLuke TennieShrinkingSeanApple TV+Olivia WashingtonI'm a VirgoFloraPrime VideoJessica WilliamsShrinkingGabyApple TV+2024Nava Mau Baby Reindeer Teri NetflixTadanobu AsanoShōgunKashigi YabushigeFXEnrico ColantoniEnglish TeacherGrant MorettiBetty GilpinThree WomenLinaStarzChloe GuidryUnder the BridgeJosephine BellHuluMoeka HoshiShōgunUsami FujiFXStephanie KoenigEnglish TeacherGwen SandersPatti LuPoneAgatha All AlongLilia CalderuDisney+Ruth NeggaPresumed InnocentBarbara SabichApple TV+Brian TeeExpatsClarke WooPrime Video2025 Erin Doherty Adolescence Briony Ariston NetflixAriyon BakareMr LovermanMorris De La RouxBBC OneBabou CeesayAlien: EarthMorrowFXSharon D ClarkeMr LovermanCarmel WalkerBBC OneTaylor DeardenThe PittDr. Melissa "Mel" KingHBO MaxStephen McKinley HendersonA Man on the InsideCalbert GrahamNetflixPoorna JagannathanDeli BoysNaveeda "Lucky"HuluXosha RoquemoreForeverShellyNetflixJenny SlateDying for SexNikki BoyerFX on HuluBen WhishawBlack DovesSam YoungNetflix

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