Odumosu is a Nigerian surname. Notable people with the surname include:
Abiola Odumosu (born 1963), Nigerian table tennis player Emmanuel Odumosu (1915–1988), known as Jesu Oyingbo, Nigerian religious sect leader David Odumosu (born 2001), Irish professional footballer Muizat Ajoke Odumosu (born 1987), Nigerian track and field athlete