TNO may refer to: Science TNO intestinal model, in gastroenterology Thai National Observatory, atop Doi Inthanon, Thailand Netherlands Organisation for Applied Scientific Research () Trans-Neptunian object, in planetology
Transport Texas and New Orleans Railroad, United States (1856–1961) Tamarindo Airport, Costa Rica (IATA:TNO)
Other uses , a French thermonuclear warhead Franco-Ténois, a Canadian francophone community The New Order: Last Days of Europe, a mod for the video game Hearts of Iron IV.