Guanare () is the capital of Portuguesa State, Venezuela. It is where la Virgen de Coromoto is said to have appeared to a Coromoto Indian.
Guanare was founded on 3 November 1591 by João Fernandes de Leão Pacheco (1543–1593), a Portuguese captain from Portimão.
Located at the edge of the Southwestern floodplains, near the Andes foothills, Guanare is in a region known for livestock and agricultural production. Guanare is also the location of one of the campuses of UNELLEZ
Notable people Javier Bertucci, philanthropist and businessman Ivian Sarcos, Miss World 2011 Martín Pérez, baseball player Ernesto Mejía (Baseballer)
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