Baby Jane may refer to:

Books What Ever Happened to Baby Jane (novel), a 1960 novel by Henry Farrell Baby Jane, a novel by Finnish writer Sofi Oksanen

Persons Baby Jane Holzer (born Jane Bruckenfeld, 1940), American fashion model and Warhol superstar of the 1960s Juanita Quigley (1931–2017), American actress billed as "Baby Jane" in several early roles Sofia Bella Galuz (born August 1, 2001), American musician and producer known as "Baby Jane" professionally.

Film, television and video games What Ever Happened to Baby Jane (1962 film), a film based on the novel, starring Bette Davis and Joan Crawford What Ever Happened to Baby Jane (1991 film), a remake based on the novel, starring Vanessa Redgrave and Lynn Redgrave Baby Jane Hudson, a character from the above work Baby Jane, a Splicer model in the video games BioShock and BioShock 2

Music "Baby Jane", song from Midnight Rave With The Pleazers EP written Dello, Cane "Baby Jane" (Rod Stewart song), 1983 "Baby Jane" (Dr. Feelgood song), 1977 Baby Jane (EP), an EP by Honey Is Cool Baby Jane, Christina Aguilera's alias for the 2006 album Back to Basics